Information
Catalog number
MBS621181
Full name
ADAM17 (CD156b, Disintegrin and Metalloproteinase Domain-containing Protein 17, TNF-alpha-converting Enzyme, TNF-alpha Convertase, Snake Venom-like Protease, CSVP, TACE)[ADAM17]
Size
NA
Price
5.00 €
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Products_type
Antibody
Reactivity
Human, Mouse, Rat
Description
The ADAM17 (CD156b, Disintegrin Metalloproteinase Domain- Protein 17, TNF-alpha-converting Enzyme, TNF-alpha Convertase, Snake Venom-like Protease, CSVP, TACE)[ADAM17] is a α- or alpha protein sometimes glycoprotein present in blood.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.