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Flt1 N-Terminal His Tag - Active Enzyme

Information

Catalog number

X1758E

Full name

Flt1 N-Terminal His Tag - Active Enzyme

Size

10 μg

Price

426.00 €

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Details

Category

Proteins & Peptides

Long description

Receptor for VEGF, VEGFB and PGF. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. Isoform SFlt1 may have an inhibitory role in angiogenesis._x000B__x000B_Description: Human recombinant Flt1 (FMS-like tyrosine kinase), also known as VEGFR1 (Vascular endothelial growth factor receptor 1), GenBank Accession No. AF063657, a.a. 783-end with N-terminal His tag, MW=67.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Antibody come from

Rabbit polyclonal AIM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human AIM.

Other description

Provided as solution in phosphate buffered saline with 0.02% sodium azide.

Clone

not specified

Antigen-antibody binding interaction

Flt1 N-Terminal His Tag - Active Enzyme

Antibody is raised in

Sf9 cells

Antibody's reacts with

Human

Antibody's reacts with these species

This antibody doesn't cross react with other species

Antibody's specificity

No Data Available

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Antibody's suited for

AIM antibody can be used for the detection of AIM by Western blot at 1 Ð 2 ug/ml. Optimal concentration should be evaluated by serial dilutions.

Storage

-20ºC

Relevant references

1)Miyazaki T, Hirokami Y, Matsuhashi N, et al. Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily. J. Exp. Med. 1999; 189:413-22._x000B_2) Biancone L, Bowen MA, Lim A, et al. Identification of a novel inducible cell-surface ligand of CD5 on activated lymphocytes. J. Exp. Med. 1996; 184:811-9._x000B_3) Haruta I, Kato Y, Hashimoto E, et al. Association of AIM, a novel apoptosis inhibitory factor, with hepatitis via supporting macrophage survival and enhancing phagocytic function of macrophages. J. Biol. Chem. 2001; 276:22910-4_x000B_4) Kuwata K, Watanabe H, Jiang S-Y, et al. AIM inhibits apoptosis of T cells and NKT cells in Corynebacterium-induced granuloma formation in mice. Am. J. Path. 2003; 162:837-47.

Protein number

see ncbi

Warnings

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.

Description

Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

Conjugation

histidine