Information
Catalog number
X1759E
Full name
Flt3 N-Terminal HIS Tag - Active Enzyme
Size
10 μg
Price
426.00 €
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Category
Proteins & Peptides
Long description
Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins._x000B__x000B_Description: Human Flt3 (GenBank Accession No. NM_004119), (a.a. 564-end) with N-terminal His tag, MW=54.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Antibody come from
Rabbit polyclonal Caspase-2 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-2.
Other description
Provided as solution in phosphate buffered saline with 0.02% sodium azide.
Clone
not specified
Antigen-antibody binding interaction
Flt3 N-Terminal HIS Tag - Active Enzyme
Antibody is raised in
Sf9 cells
Antibody's reacts with
Human
Antibody's reacts with these species
This antibody doesn't cross react with other species
Antibody's specificity
No Data Available
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Antibody's suited for
Caspase-2 antibody can be used for the detection of caspase-2 by Western blot at 1 ug/ml. Depending on cell lines or tissues used, other cleavage products may be observed. Optimal concentration should be evaluated by serial dilutions.
Storage
-20ºC
Relevant references
1) Martinon F and Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases.Cell 2004; 117:561-74_x000B_2) Zhivotovsky B and Orrenius S. Caspase-2 funtion in response to DNA damage.Biochim. Biophys. Res. Comm. 2005; 331:859-67._x000B_3) Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 converting enzyme Science 1995; 267:2000-3_x000B_4) Gracie JA, Robertson SE, and McInnes IB. Interleukin-18. J. Leukoc. Biol. 2003; 73:213-224.
Protein number
see ncbi
Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.
Conjugation
histidine