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Flt3 N-Terminal HIS Tag - Active Enzyme

Information

Catalog number

X1759E

Full name

Flt3 N-Terminal HIS Tag - Active Enzyme

Size

10 μg

Price

426.00 €

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Details

Category

Proteins & Peptides

Long description

Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins._x000B__x000B_Description: Human Flt3 (GenBank Accession No. NM_004119), (a.a. 564-end) with N-terminal His tag, MW=54.2 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Antibody come from

Rabbit polyclonal Caspase-2 antibody was raised against a 16 amino acid peptide from the amino-terminus of human Caspase-2.

Other description

Provided as solution in phosphate buffered saline with 0.02% sodium azide.

Clone

not specified

Antigen-antibody binding interaction

Flt3 N-Terminal HIS Tag - Active Enzyme

Antibody is raised in

Sf9 cells

Antibody's reacts with

Human

Antibody's reacts with these species

This antibody doesn't cross react with other species

Antibody's specificity

No Data Available

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Antibody's suited for

Caspase-2 antibody can be used for the detection of caspase-2 by Western blot at 1 ug/ml. Depending on cell lines or tissues used, other cleavage products may be observed. Optimal concentration should be evaluated by serial dilutions.

Storage

-20ºC

Relevant references

1) Martinon F and Tschopp J. Inflammatory caspases: linking an intracellular innate immune system to autoinflammatory diseases.Cell 2004; 117:561-74_x000B_2) Zhivotovsky B and Orrenius S. Caspase-2 funtion in response to DNA damage.Biochim. Biophys. Res. Comm. 2005; 331:859-67._x000B_3) Kuida K, Lippke JA, Ku G, et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 converting enzyme Science 1995; 267:2000-3_x000B_4) Gracie JA, Robertson SE, and McInnes IB. Interleukin-18. J. Leukoc. Biol. 2003; 73:213-224.

Protein number

see ncbi

Warnings

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.

Description

Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

Conjugation

histidine