Information
Catalog number
MBS621619
Full name
BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Size
100ul
Price
630.00 €
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Alternative name1
Anti-BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Alternative name2
BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Alternative name3
BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Alternative name4
BACE, Asp2
Alternative name5
Anti -BACE, Asp2 (CT) (Memapsin2, Beta-site APP Cleaving Enzyme, Aspartyl Protease 2)
Other names
beta-secretase 1 isoform D preproprotein; Beta-secretase 1; beta-secretase 1; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; beta-site APP cleaving enzyme 1; beta-secretase 1 precursor variant 1; transmembrane aspartic proteinase Asp2; membrane-associated aspartic protease 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme; beta-site APP-cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2
Gene name
N/A
Gene name synonims
N/A
Other gene names
BACE1; BACE1; ASP2; BACE; HSPC104; BACE; KIAA1149; ASP2; Asp 2
Category
Antibodies
Clonality
Polyclonal
Immunoglobulin isotype
IgG
Clone
Polyclonal antibody
Host organism
Host: Goat; Source: Human
Species reactivity
Human
Specificity and cross-reactivity
Recognizes human beta amyloid cleaving enzyme (BACE), a 70kD aspartic protease. BACE is involved in the cleavage of the amyloid precursor protein (APP) to generate amyloid beta peptide. Cerebral deposition of amyloid beta peptide is an early feature of Alzheimer's disease.
Purification method
Serum.
Form/Appearance
Serum. Supplied as a liquid with 0.1% sodium azide.
Concentration
N/A
Storage and shipping
Store productone at -20 degrees Celsius.
Tested for:
Immunohistochemistry (IHC)
Description
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
Advisory
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Additional description
Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.