Information

Catalog number

MBS641990

Full name

TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met

Size

100ug

Price

724.00 €

Go to shop   

Details

Alternative name1

Anti-TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met

Alternative name2

TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met

Alternative name3

TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met

Alternative name4

TACE

Alternative name5

Anti -TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met

Other names

tace, isoform A; N/A; CG7908 gene product from transcript CG7908-RB; CG7908-PA; CG7908-PB; Tace-PA; Tace-PB; tace; N/A; N/A

Gene name

N/A

Gene name synonims

N/A

Other gene names

Tace; N/A; CG7908; CT23908; DmelCG7908; DTACE; TACE; N/A

Category

Antibodies

Clonality

Polyclonal

Immunoglobulin isotype

IgG

Clone

Polyclonal antibody

Host organism

Host: Goat; Source: Human

Species reactivity

Human

Specificity and cross-reactivity

Recognizes human CD156b (C-TERMINAL). Species sequence homology: chicken, hamster and rat.

Purification method

Affinity Purified by immunoaffinity chromatography.

Form/Appearance

Supplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

N/A

Storage and shipping

Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested for:

ELISA (EL/EIA), Western Blot (WB)

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Tissue

tumor

Additional description

The TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme) ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met is a α- or alpha protein sometimes glycoprotein present in blood.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.