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Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263), ALEXA Fluor 594

Information

Catalog number

GENTObs-12955R-A594

Full name

Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263), ALEXA Fluor 594

Size

100 microliters

Price

516.00 €

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Details

Type

Conjugated Primary Antibody

Conjugated with

ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Target Protein/Peptide

Acetyl Coenzyme A Carboxylase alpha Ser1263

Specificity

This antibody reacts specifically with Acetyl Coenzyme A Carboxylase alpha (Ser1263)

Modification

Phosphorylation

Modification site

Ser1263

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Concentration

1ug per 1ul

Subcellular locations

N/A

Antigen Source

KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser1263

Gene ID

N/A

Swiss Prot

N/A

Applications

IF(IHC-P)

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Cross reactive species

Human (Homo sapiens)

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Background information

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Purification method

Purified by Protein A.

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Excitation emission

590nm/617nm

Synonyms

Acetyl Coenzyme A Carboxylase alpha phospho S1263; p-Acetyl Coenzyme A Carboxylase alpha phospho S1263; ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC; ACC-alpha; ACC1; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha.

Also known as

Acetyl Coenzyme A Carboxylase alpha (Ser1263) Antibody

Other name

Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263)

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Description

N terminal acetylation or CH3CO as epigenetic regulation of Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263) by NATs.The Anti-Acetyl Coenzyme A Carboxylase alpha (Ser1263) is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

For facs or microscopy Alexa 1 conjugate.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1