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Anti-E1 Ubiquitin Activating Enzyme, ALEXA Fluor 594

Information

Catalog number

GENTObs-6835R-A594

Full name

Anti-E1 Ubiquitin Activating Enzyme, ALEXA Fluor 594

Size

100 microliters

Price

489.00 €

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Details

Type

Conjugated Primary Antibody

Conjugated with

ALEXA FLUOR® 594

Host organism

Rabbit (Oryctolagus cuniculus)

Target Protein/Peptide

E1 Ubiquitin Activating Enzyme

Specificity

This antibody reacts specifically with E1 Ubiquitin Activating Enzyme

Modification

No modification has been applied to this antibody

Modification site

None

Clonality

Polyclonal Antibody

Clone

Polyclonal Antibodies

Concentration

1ug per 1ul

Subcellular locations

N/A

Antigen Source

KLH conjugated synthetic peptide derived from human UBE1

Gene ID

7317

Swiss Prot

N/A

Applications

IF(IHC-P)

Applications with corresponding dilutions

IF(IHC-P)(1:50-200)

Cross reactive species

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)

Cross Reactive Species details

No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.

Background information

The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008].

Purification method

Purified by Protein A.

Storage

Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.

Excitation emission

590nm/617nm

Synonyms

A1S9; A1S9 protein; A1S9T and BN75 temperature sensitivity complementing; A1S9T; A1ST; GXP 1; GXP1; MGC4781; Protein A1S9; Uba1; UBA1_HUMAN; UBE 1 ; UBE 1X; UBE1; UBE1X; Ubiquitin activating enzyme E1; Ubiquitin-activating enzyme E1; Ubiquitin-like modier-activating enzyme 1.

Also known as

E1 Ubiquitin Activating Enzyme Antibody

Other name

Anti-E1 Ubiquitin Activating Enzyme

Advisory

Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Properties

For facs or microscopy Alexa 1 conjugate.

Conjugation

Alexa Fluor,ALEXA FLUOR® 594

Conjugated

Alexa conjugate 1

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.