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BACE1, Ectodomain (Beta-site APP Cleaving Enzyme)

Information

Catalog number

GEN601607

Full name

BACE1, Ectodomain (Beta-site APP Cleaving Enzyme)

Size

100ug

Price

691.00 €

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Details

Also known as

BACE1, Ectodomain

Other names

beta-secretase 1 isoform 2; Beta-secretase 1; beta-secretase 1; ASP2; asp 2; memapsin-2; APP beta-secretase; aspartyl protease 2; membrane-associated aspartic protease 2; beta-site amyloid precursor protein cleaving enzyme 1; beta-site APP cleaving enzyme 1; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2

Category

Antibodies

Subcategory

Mnoclonal antibodies

Gene name

Bace1; Bace1; C76936; Bace; ASP2; Asp 2

Gene name synonims

Bace1; Bace1; C76936; Bace; ASP2; Asp 2

Other gene names

Bace1; Bace1; C76936; Bace; ASP2; Asp 2

Clonality

Monoclonal

Immunoglobulin isotype

IgG1

Clone

8H106

Host organism

Mouse (Mus musculus)

Source organism

Human (Homo sapiens)

Species reactivity

Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Specificity and cross-reactivity

Recognizes human BACE1 ectodomain. Species Crossreactvity: mouse. Does not react with human or mouse BACE2, human ADAM8, ADAM9, ADAM10, ADAM15 or TACE.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Purification method

Affinity Purified by Protein G affinity chromatography. Endotoxin:

Form/Appearance

Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 200ul sterile PBS.

Concentration

N/A

Storage and shipping

Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Tested applications:

ELISA (EL/EIA), Immunoprecipitation (IP), Neutralization

Description

Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.