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Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE) antiserum

Information

Catalog number

TACE11-S

Full name

Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE) antiserum

Size

100 ul

Price

439.00 €

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Details

Stock availability

Available

Category

Primary Antibodies

Antibody type

Polyclonal Antibody

Antibody host

Rabbit

Antibody conjugate

N/A

Technical datasheet

Contact Gentaur to request the datasheet or ask our specialists for more information.

Notes

The Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE) antiserum is manufactured for Research Use Only or for diagnostics purposes.

Description

The Rabbit Anti- TNF-alpha Converting Enzyme (TACE) antiserum is a α- or alpha protein sometimes glycoprotein present in blood.This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

About

Rabbits are used for polyclonal antibody production by adi. Rabbit antibodies are very stable and can be stored for several days at room temperature. adi adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Latin name

Oryctolagus cuniculus,Rattus norvegicus

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.