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Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1)

Information

Catalog number

X2230P

Full name

Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1)

Size

50 μg

Price

517.00 €

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Details

Category

Primary Antibodies

Long description

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

Antibody come from

N-terminal region of human

Other description

Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification

Clone

Polyclonal

Antigen-antibody binding interaction

Rabbit anti Beta-site APP-Cleaving Enzyme 1 (BACE1) Antibody

Antibody is raised in

Rabbit

Antibody's reacts with

Human

Antibody's reacts with these species

This antibody doesn't cross react with other species

Antibody's specificity

No Data Available

Application

Immunohistochemistry-Paraffin

Antibody's suited for

Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (10-15 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Storage

Long term: -70ºC; Short term: +4ºC

Relevant references

no information yet

Protein number

see ncbi

Warnings

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

About

Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Latin name

Oryctolagus cuniculus