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TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met[TACE]

Information

Catalog number

MBS641990

Full name

TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin and Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme), ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met[TACE]

Size

NA

Price

5.00 €

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Details

Products_type

Antibody

Reactivity

Human

Tissue

tumor

Description

The TACE, CT (Tumor Necrosis Factor alpha Converting Enzyme, TNF alpha Convertase, TNF alpha Converting Enzyme, A Disintegrin Metalloproteinase Domain 17 (Tumor Necrosis Factor, alpha, Converting Enzyme) ADAM 17, ADAM17, ADAM-17, ADAM17 Protein, ADAM Met[TACE] is a α- or alpha protein sometimes glycoprotein present in blood.Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Gene

Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.